Understanding Retinopathy of Prematurity (ROP)
Retinopathy of Prematurity (ROP) is a vasoproliferative eye disorder affecting the blood vessels of the retina (the light-sensitive screen at the back of the eye) in premature infants. ROP is a major cause of preventable childhood blindness worldwide.
Which Infants Are at Risk?
ROP typically affects the youngest, smallest, and sickest infants. Screening is highly recommended for:
- Babies born at or before 34 weeks of gestation.
- Babies with a birth weight of 2000 grams (4.4 pounds) or less.
- Premature infants with systemic complications like severe breathing difficulties, heart conditions, repeated blood transfusions, or sepsis.
Why Does ROP Develop?
During a normal full-term pregnancy, retinal blood vessels finish developing at birth. When a baby is born early, this growth stalls because the vessels are not fully formed.
As the baby grows, the oxygen-deprived outer retina sends out signals requesting new blood vessels. This triggers the growth of abnormal, fragile new blood vessels (neovascularization). These weak vessels can leak fluid, bleed, and generate scar tissue, which can pull the retina away from the back of the eye, causing a retinal detachment.
Stages and Treatment of ROP
ROP is classified into 5 stages depending on the severity of vessel growth:
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Stage 1 & 2:
Mild abnormal growth. These stages often regress and heal on their own without treatment, but require regular weekly monitoring.
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Stage 3:
Severe abnormal blood vessels. If accompanied by "plus disease" (dilated, twisted vessels in the back), urgent laser photocoagulation is required to ablate the outer retina and stop the abnormal vessel signals.
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Stage 4 & 5:
Partial (Stage 4) or complete (Stage 5) retinal detachment. This requires major vitreo-retinal surgery to attempt to salvage central sight. If untreated, it leads to permanent blindness.
* Golden Rule of ROP: The first eye checkup must be done within 4 weeks (28 days) of birth. ROP does not show any external signs like redness or swelling; it can only be detected via a dilated fundus exam performed by a trained specialist.
At Utsav Eye Clinic, we provide expert screening and management protocols for ROP in Kharghar, working closely with local Neonatal Intensive Care Units (NICUs) to protect premature infants' sight.

